Prior to joining Interline, Mario most recently served as Director of Computational Chemistry at Nurix working on modulators of protein-protein interactions, including bifunctional degraders. Mario also has over 20 year of experience in small molecule drug discovery at Amgen, Tularik, and Boehringer Ingelheim. He has expertise applying a range of CADD methods to a diversity of drug targets, and experience in multiple therapeutics areas. Mario has also developed ligand affinity scoring functions, cheminformatics tools and several ADMET predictive models to support lead identificaiton and lead optimization. Mario was directly involved in the identification of 12 drug candidates and 3 that advanced into clinical studies. Mario received a Pharm.D. as well as an M.S. in physical organic chemistry from the National University of Cordoba and a Ph.D. in Medicinal Chemistry from the University of Buenos Aires, both in Argentina. Mario completed his postdoctoral training in CADD as an NIH-Fogarty Fellow at The University of Illinois at Chicago.
VP, Computational Chemistry